منابع مشابه
Brown adipose tissue
Obesity is currently a global pandemic, and is associated with increased mortality and co-morbidities including many metabolic diseases. Obesity is characterized by an increase in adipose mass due to increased energy intake, decreased energy expenditure, or both. While white adipose tissue is specialized for energy storage, brown adipose tissue has a high concentration of mitochondria and uniqu...
متن کاملVisualization of Brown Adipose Tissue
1Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2Molecular Epidemiology, Graduate School of Medicine, Kobe University, Kobe, Japan; 3First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan; 4Biology Laboratory Research Center, Daiichi Radioisotope Laboratories, Limited, Chiba, Japan; and 5Department of Anatomy, Meiji Colleg...
متن کاملBrown Adipose Tissue in Hamsters
The effect of acclimation at different temperatures on the act iv i ty of interscapular brown adipose tissue has been i nves t i ga ted in the hamster, a h ibernator . Between 3l ~ and ~~ the cytochrome oxidase act iv i ty of the tissue increased z~_ to 5-fold, mitochondrial GDP binding per mg of mitochondrial protein doubled, and the amount of uncoupling protein rose from 1.7% to 5.4% of total...
متن کاملRenaissance of brown adipose tissue.
The recent discovery of functional brown adipose tissue in human adults raised this tissue again into the focus of current investigations concerning human energy homeostasis. Brown fat is a key thermogenic tissue and is essential for non-shivering thermogenesis in the human newborn and hibernating mammals. This review highlights the biological and molecular aspects of brown adipose tissue devel...
متن کاملBrown adipose tissue and thermogenesis.
The growing understanding of adipose tissue as an important endocrine organ with multiple metabolic functions has directed the attention to the (patho)physiology of distinct fat depots. Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate significant amounts of chemical energy through uncoupled respiration and heat production (thermogenesis). This process is mediated by...
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ژورنال
عنوان ژورنال: Circulation
سال: 2012
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.111.042929